Basic Information
ID: ALA4341891
Type: Binding
Description: Antagonist activity at mouse P2X7 receptor assessed as inhibition of BzATP-induced YO PRO dye uptake preincubated for 20 mins followed by YO PRO dye and BzATP addition measured after 30 mins by fluorescence assay
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4341891
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 441.88 | 4.11 | 4.11 |
| 445.01 | 3.70 | 3.70 |
| 460.02 | 4.16 | 4.16 |
| 425.88 | 4.99 | 4.99 |
| 425.88 | 4.99 | 4.99 |
| 419.93 | 4.11 | 4.11 |
| 441.88 | 4.11 | 4.11 |