Basic Information
ID: ALA4342147
Type: Functional
Description: Anti-hypersensitive activity in MCT-induced pulmonary arterial hypertension Sprague-Dawley rat model assessed as pulmonary artery medial thickness at 37.5 mg/kg, po administered daily for 14 days starting from 14 days post-MCT challenge and measured post-last dose in presence of DCA by hematoxylin and eosin staining-based microscopic analysis (Rvb = 0.41 +/- 0.051 No_unit)
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA4342147
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.30 | 1.22 | 1.22 |