Anti-hypersensitive activity in MCT-induced pulmonary arterial hypertension Sprague-Dawley rat model assessed as reduction in cardiomyocyte hypertroph...

Basic Information

ID: ALA4342152

Type: Functional

Description: Anti-hypersensitive activity in MCT-induced pulmonary arterial hypertension Sprague-Dawley rat model assessed as reduction in cardiomyocyte hypertrophy by measuring cross-sectional area of cardiomyocyte at 43.3 mg/kg, po administered daily for 14 days starting from 14 days post-MCT challenge and measured post-last dose by hematoxylin and eosin staining-based microscopic analysis (Rvb = 418 +/- 50.88 micrometer2)

Format: BAO_0000218

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Target:  Rattus norvegicus(ALA376)

Document:  ALA4340557

Anti-hypersensitive activity in MCT-induced pulmonary arterial hypertension Sprague-Dawley rat model assessed as reduction in cardiomyocyte hypertrophy by measuring cross-sectional area of cardiomyocyte at 43.3 mg/kg, po administered daily for 14 days starting from 14 days post-MCT challenge and measured post-last dose by hematoxylin and eosin staining-based microscopic analysis (Rvb = 418 +/- 50.88 micrometer2): 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
420.321.221.22