Basic Information
ID: ALA4342157
Type: Functional
Description: Anti-hypersensitive activity in MCT-induced pulmonary arterial hypertension Sprague-Dawley rat model assessed as reduction in cardiomyocyte hypertrophy by measuring cardiac fibrosis at 37.5 mg/kg, po administered daily for 14 days starting from 14 days post-MCT challenge and measured post-last dose in presence of DCA by Masson's trichrome staining-based microscopic analysis (Rvb = 11.74 +/- 3.24 %)
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA4342157
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.30 | 1.22 | 1.22 |