Basic Information
ID: ALA4342603
Type: Binding
Description: Inhibition of BACE1 in human SH-SY5Y cells transfected with APP695 assessed as reduction in amyloidbeta (1 to 40 residues) incubated for 24 hrs by sandwich ELlSA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: SH-SY5Y
Target: Beta-secretase 1(ALA4822)
Document: ALA4342403
Inhibition of BACE1 in human SH-SY5Y cells transfected with APP695 assessed as reduction in amyloidbeta (1 to 40 residues) incubated for 24 hrs by sandwich ELlSA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4342603
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 492.46 | 3.88 | 3.88 |
| 504.50 | 2.38 | 2.38 |
| 461.47 | 3.27 | 3.27 |
| 504.46 | 4.42 | 4.42 |