Basic Information
ID: ALA4342608
Type: ADME
Description: Inhibition of C-terminal His6-tagged human BACE2 expressed in mammalian expression system preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRET assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Beta secretase 2(ALA2525)
Document: ALA4342403
Inhibition of C-terminal His6-tagged human BACE2 expressed in mammalian expression system preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4342608
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.47 | 1.90 | 1.90 |
| 463.82 | 3.52 | 3.52 |
| 447.44 | 2.63 | 2.63 |
| 459.86 | 3.77 | 3.77 |
| 460.51 | 2.87 | 2.87 |