Basic Information
ID: ALA4342632
Type: Functional
Description: In vivo inhibition of BACE1 in Sprague Dawley rat assessed as reduction in amyloidbeta 40 level in CSF at 10 mg/kg, po measured at 4 hrs post dose by sandwich ELISA relative to control
Organism: Rattus norvegicus
Strain: Sprague Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA4342632
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.47 | 1.90 | 1.90 |
| 464.95 | 3.36 | 3.36 |
| 460.51 | 2.87 | 2.87 |