In vivo inhibition of BACE1 in Sprague Dawley rat assessed as reduction in amyloidbeta 40 level in CSF at 10 mg/kg, po measured at 4 hrs post dose by ...

Basic Information

ID: ALA4342632

Type: Functional

Description: In vivo inhibition of BACE1 in Sprague Dawley rat assessed as reduction in amyloidbeta 40 level in CSF at 10 mg/kg, po measured at 4 hrs post dose by sandwich ELISA relative to control

Format: BAO_0000218

Organism: Rattus norvegicus

Strain: Sprague Dawley

Target: Rattus norvegicus(ALA376)

Document: ALA4342403

In vivo inhibition of BACE1 in Sprague Dawley rat assessed as reduction in amyloidbeta 40 level in CSF at 10 mg/kg, po measured at 4 hrs post dose by sandwich ELISA relative to control: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4342632

Inhibition

Total(3)

Parent Molecular Weight	ALogP	Polar Surface Area
447.47	1.90	1.90
464.95	3.36	3.36
460.51	2.87	2.87

Parent Molecular Weight

ALogP

Polar Surface Area

447.47

1.90

464.95

3.36

460.51

2.87

In vivo inhibition of BACE1 in Sprague Dawley rat assessed as reduction in amyloidbeta 40 level in CSF at 10 mg/kg, po measured at 4 hrs post dose by ...

Basic Information

Activity Charts

Compound Summary