Basic Information
ID: ALA4342649
Type: Functional
Description: In vivo inhibition of BACE1 in Beagle dog assessed as reduction in amyloidbeta (1 to 42 residues) at 0.31 mg/kg, po measured at 8 hrs post dose relative to baseline
Organism: Canis lupus familiaris
Strain: Beagle
Activity Charts
Bioactivity
Activity Types for Assay ALA4342649
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 432.46 | 2.87 | 2.87 |
| 484.50 | 2.90 | 2.90 |