Basic Information
ID: ALA4342651
Type: Binding
Description: Inhibition of BACE1 in human SK-N-BE(2) cells expressing human APP695 assessed as reduction in amyloidbeta (1 to 42 residues) level incubated for 18 hrs by sandwich ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4342651
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 395.44 | 3.38 | 3.38 |
| 432.46 | 2.87 | 2.87 |
| 484.50 | 2.90 | 2.90 |