Inhibition of BACE1 in human SK-N-BE(2) cells expressing human APP695 assessed as reduction in amyloidbeta (1 to 42 residues) level incubated for 18 h...

Basic Information

ID: ALA4342651

Type: Binding

Description: Inhibition of BACE1 in human SK-N-BE(2) cells expressing human APP695 assessed as reduction in amyloidbeta (1 to 42 residues) level incubated for 18 hrs by sandwich ELISA

Format: BAO_0000219

Organism: Homo sapiens

Target: Beta-secretase 1(ALA4822)

Document: ALA4342403

Inhibition of BACE1 in human SK-N-BE(2) cells expressing human APP695 assessed as reduction in amyloidbeta (1 to 42 residues) level incubated for 18 hrs by sandwich ELISA: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4342651

IC50

Total(3)

Parent Molecular Weight	ALogP	Polar Surface Area
395.44	3.38	3.38
432.46	2.87	2.87
484.50	2.90	2.90

Parent Molecular Weight

ALogP

Polar Surface Area

395.44

3.38

432.46

2.87

484.50

2.90

Inhibition of BACE1 in human SK-N-BE(2) cells expressing human APP695 assessed as reduction in amyloidbeta (1 to 42 residues) level incubated for 18 h...

Basic Information

Activity Charts

Compound Summary