Basic Information
ID: ALA4343017
Type: Binding
Description: Inhibition of human recombinant full length N-terminal GST-tagged PDE4B1 expressed in baculovirus infected Sf9 cells at 10'-5 M using cAMP as substrate incubated for 20 mins followed by substrate addition by luciferase assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Phosphodiesterase 4B(ALA275)
Document: ALA4342411
Inhibition of human recombinant full length N-terminal GST-tagged PDE4B1 expressed in baculovirus infected Sf9 cells at 10'-5 M using cAMP as substrate incubated for 20 mins followed by substrate addition by luciferase assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4343017
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 275.35 | 2.62 | 2.62 |
| 520.63 | 3.30 | 3.30 |
| 480.57 | 2.82 | 2.82 |
| 573.52 | 5.43 | 5.43 |
| 452.52 | 1.60 | 1.60 |
| 548.68 | 4.52 | 4.52 |
| 466.54 | 1.99 | 1.99 |
| 587.55 | 5.82 | 5.82 |
| 494.59 | 3.21 | 3.21 |
| 506.61 | 2.91 | 2.91 |
| 534.66 | 4.13 | 4.13 |
| 519.43 | 4.12 | 4.12 |
| 533.46 | 4.51 | 4.51 |