Basic Information
ID: ALA4343069
Type: Toxicity
Description: Selectivity index, ratio of Ki for inhibition of human NMT1 R295Q/W297F/A452M/L453V/L462V/N473H/L495M/Q496L mutant expressed in Escherichia coli Rosetta-2 cells to Ki for inhibition of N-terminal TEV cleavage site-fused His6 tagged Leishmania major NMT (11 to 421 residues) expressed in Escherichia coli Rosetta-2 cells
Activity Charts
Bioactivity
Activity Types for Assay ALA4343069
Ratio Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.34 | 3.49 | 3.49 |
| 365.43 | 3.47 | 3.47 |
| 401.90 | 3.46 | 3.46 |