Basic Information
ID: ALA4343116
Type: Binding
Description: Inhibition of perforin (unknown origin) assessed as reduction in perforin-mediated cell lysis in human Jurkat T cells incubated for 30 mins by 51Cr release based gamma counting method
Organism: Homo sapiens
Cell type: Jurkat
Activity Charts
Bioactivity
Activity Types for Assay ALA4343116
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 537.58 | 4.18 | 4.18 |
| 530.55 | 5.28 | 5.28 |
| 560.58 | 5.29 | 5.29 |
| 484.51 | 4.19 | 4.19 |
| 594.71 | 6.00 | 6.00 |
| 596.68 | 4.84 | 4.84 |
| 609.72 | 4.76 | 4.76 |
| 580.68 | 5.61 | 5.61 |
| 530.55 | 5.28 | 5.28 |
| 498.54 | 4.54 | 4.54 |
| 557.60 | 3.87 | 3.87 |
| 528.56 | 4.55 | 4.55 |
| 484.51 | 4.19 | 4.19 |
| 541.60 | 4.89 | 4.89 |
| 554.64 | 5.07 | 5.07 |