Basic Information
ID: ALA4343117
Type: Binding
Description: Inhibition of perforin in human KHYG-1 cells pre-treated with compound for 20 mins assessed as reduction in KHYG-1 cells-mediated cell lysis of human K562 cells measured after 4 hrs by 51Cr release based gamma counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4343117
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 537.58 | 4.18 | 4.18 |
| 530.55 | 5.28 | 5.28 |
| 560.58 | 5.29 | 5.29 |
| 484.51 | 4.19 | 4.19 |
| 530.55 | 5.28 | 5.28 |
| 498.54 | 4.54 | 4.54 |
| 528.56 | 4.55 | 4.55 |