Basic Information
ID: ALA4343119
Type: Binding
Description: Inhibition of perforin in human KHYG-1 cells pre-treated with compound for 20 mins assessed as reduction in KHYG-1 cells-mediated cell lysis of human K562 cells at 20 uM measured after 4 hrs by 51Cr release based gamma counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4343119
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 530.55 | 5.28 | 5.28 |
| 484.51 | 4.19 | 4.19 |
| 594.71 | 6.00 | 6.00 |
| 596.68 | 4.84 | 4.84 |
| 609.72 | 4.76 | 4.76 |
| 580.68 | 5.61 | 5.61 |
| 557.60 | 3.87 | 3.87 |
| 541.60 | 4.89 | 4.89 |
| 554.64 | 5.07 | 5.07 |