Basic Information
ID: ALA4344213
Type: Binding
Description: Antagonist activity at human CCR8 expressed in CHOK1 cells assessed as inhibition in CCL1-induced beta-arrestin 2 recruitment at 20 uM incubated for 30 mins followed by CCL1 addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4344213
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 354.45 | 2.65 | 2.65 |
| 354.45 | 2.95 | 2.95 |
| 310.40 | 2.62 | 2.62 |
| 514.62 | 5.23 | 5.23 |
| 509.44 | 6.01 | 6.01 |
| 379.55 | 4.71 | 4.71 |
| 342.44 | 2.79 | 2.79 |
| 561.48 | 5.42 | 5.42 |
| 480.62 | 4.44 | 4.44 |