Basic Information
ID: ALA4344228
Type: Binding
Description: Antagonist activity at human Gq-coupled HRH1 expressed in CHOK1 cells assessed as inhibition in Orexin A-induced beta-arrestin 2 recruitment incubated for 30 mins followed by Orexin A addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Histamine H1 receptor(ALA231)
Document: ALA4342456
Antagonist activity at human Gq-coupled HRH1 expressed in CHOK1 cells assessed as inhibition in Orexin A-induced beta-arrestin 2 recruitment incubated for 30 mins followed by Orexin A addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4344228
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 509.44 | 6.01 | 6.01 |