Basic Information
ID: ALA4344229
Type: Binding
Description: Antagonist activity at human Gq-coupled NPSR1b expressed in human U2OS cells assessed as inhibition in neuropeptide S-induced beta-arrestin 2 recruitment incubated for 30 mins followed by neuropeptide S addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: U2OS
Target: Neuropeptide S receptor(ALA5162)
Document: ALA4342456
Antagonist activity at human Gq-coupled NPSR1b expressed in human U2OS cells assessed as inhibition in neuropeptide S-induced beta-arrestin 2 recruitment incubated for 30 mins followed by neuropeptide S addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4344229
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 509.44 | 6.01 | 6.01 |
| 561.48 | 5.42 | 5.42 |