Basic Information
ID: ALA4344233
Type: Binding
Description: Antagonist activity at human Gs/Gi/o-coupled CHRM4 expressed in CHOK1 cells assessed as inhibition in acetylcholine-induced beta-arrestin 2 recruitment incubated for 30 mins followed by acetylcholine addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Muscarinic acetylcholine receptor M4(ALA1821)
Document: ALA4342456
Antagonist activity at human Gs/Gi/o-coupled CHRM4 expressed in CHOK1 cells assessed as inhibition in acetylcholine-induced beta-arrestin 2 recruitment incubated for 30 mins followed by acetylcholine addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4344233
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 480.62 | 4.44 | 4.44 |