Basic Information
ID: ALA4344322
Type: Binding
Description: Selectivity index, ratio of Ki for inhibition of N-terminal His6-tagged human Bcl-xL (with internal deletion of 45 to 85 amino acids and C-terminal truncation for 212 to 233 residues) expressed in Escherichia coli Rosetta2 DE3 to KI for inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3
Format: BAO_0000019
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4342462
Selectivity index, ratio of Ki for inhibition of N-terminal His6-tagged human Bcl-xL (with internal deletion of 45 to 85 amino acids and C-terminal truncation for 212 to 233 residues) expressed in Escherichia coli Rosetta2 DE3 to KI for inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4344322
Ratio Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 413.52 | 4.52 | 4.52 |
| 463.58 | 5.67 | 5.67 |
| 497.64 | 4.20 | 4.20 |
| 553.75 | 5.50 | 5.50 |
| 596.78 | 5.28 | 5.28 |
| 583.78 | 5.50 | 5.50 |