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Time dependent inhibition of CYP2C19 in human liver microsomes at 10 uM preincubated for 30 mins in presence of NADPH-generating system followed by su...

Basic Information

ID: ALA4344561

Type: ADME

Description: Time dependent inhibition of CYP2C19 in human liver microsomes at 10 uM preincubated for 30 mins in presence of NADPH-generating system followed by substrate addition and measured after 10 mins by HPLC-MS/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target:  Cytochrome P450 2C19(ALA3622)

Document:  ALA4342468

Time dependent inhibition of CYP2C19 in human liver microsomes at 10 uM preincubated for 30 mins in presence of NADPH-generating system followed by substrate addition and measured after 10 mins by HPLC-MS/MS analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
363.414.584.58