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ID: ALA4344561
Type: ADME
Description: Time dependent inhibition of CYP2C19 in human liver microsomes at 10 uM preincubated for 30 mins in presence of NADPH-generating system followed by substrate addition and measured after 10 mins by HPLC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2C19(ALA3622)
Document: ALA4342468
Time dependent inhibition of CYP2C19 in human liver microsomes at 10 uM preincubated for 30 mins in presence of NADPH-generating system followed by substrate addition and measured after 10 mins by HPLC-MS/MS analysis: 1
Bioactivity
Activity Types for Assay ALA4344561
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
363.41 | 4.58 | 4.58 |