Basic Information
ID: ALA4344631
Type: Binding
Description: Binding affinity to Granzyme A in human NK92 cells at 1 uM treated 1 hr after GrA covalent inhibitor methyl 4-[(3S)-3-[[2-[(2S)-2-[(1-diphenoxyphosphoryl-4-guanidinobutyl)carbamoyl]-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-2-oxoethyl]carbamoyl]-3,4-dihydro-1H-isoquinolin-2-yl]-4-oxobutanoate dosing and measured 30 mins to 2 hrs post dose by SDS-PAGE analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4344631
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1309.65 |