Basic Information
ID: ALA4344955
Type: Binding
Description: Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as substrate preincubated for 30 mins followed by substrate addition and measured for 30 mins by fluorescence based assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Epoxide hydratase(ALA2409)
Document: ALA4342480
Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as substrate preincubated for 30 mins followed by substrate addition and measured for 30 mins by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4344955
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 449.48 | 5.71 | 5.71 |
| 378.45 | 4.09 | 4.09 |
| 492.47 | 6.29 | 6.29 |
| 365.86 | 5.03 | 5.03 |
| 321.39 | 4.95 | 4.95 |
| 442.46 | 5.41 | 5.41 |
| 406.48 | 5.13 | 5.13 |
| 415.41 | 5.28 | 5.28 |
| 424.47 | 5.27 | 5.27 |
| 349.41 | 4.52 | 4.52 |
| 399.41 | 5.40 | 5.40 |
| 442.46 | 5.41 | 5.41 |
| 424.47 | 5.27 | 5.27 |
| 450.49 | 4.87 | 4.87 |
| 492.47 | 6.29 | 6.29 |
| 424.47 | 5.27 | 5.27 |
| 345.44 | 4.69 | 4.69 |