Basic Information
ID: ALA4345131
Type: Binding
Description: Inhibition of IRAK4 in human whole blood assessed as inhibition of R848-induced IL-6 production preincubated for 90 mins followed by R848 stimulation and measured after 3.5 hrs by MSD assay
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA4345131
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 571.60 | 2.97 | 2.97 |
| 476.54 | 2.20 | 2.20 |
| 409.45 | 1.50 | 1.50 |
| 478.55 | 2.59 | 2.59 |
| 392.42 | 1.40 | 1.40 |
| 464.53 | 1.94 | 1.94 |
| 393.45 | 2.53 | 2.53 |
| 482.52 | 1.88 | 1.88 |
| 518.57 | 1.43 | 1.43 |
| 428.47 | 0.95 | 0.95 |
| 545.57 | 2.43 | 2.43 |
| 535.62 | 2.72 | 2.72 |
| 537.60 | 1.57 | 1.57 |
| 571.60 | 2.97 | 2.97 |