Assay Report Card

Basic Information

ID: ALA4345166

Type: Functional

Description: Invivo inhibition of IRAK4 in R848-induced po dosed C57BL/6 mouse assessed as inhibition of IL-6 secretion administered as nanosuspension at 1 hr prior to R848 challenge and measured after 1 hr by ELISA

Organism: Mus musculus

Strain: C57BL/6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
409.451.501.50
482.521.881.88