Assay Report Card

Basic Information

ID: ALA4345246

Type: Binding

Description: Activation of human Nav1.1 expressed in HEK293 cells assessed as ratio of compound activation AUC to baseline activation AUC at 1.11 uM at -120 mV holding potential by Qpatch assay

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1662.02
1585.92
1490.91
1646.02
1557.91
1612.01
1685.06
1557.91
1662.07
1571.94
1557.91
1597.98
1596.95
1607.97
1557.91
1680.47
1518.92
1607.97