Basic Information
ID: ALA4345255
Type: Binding
Description: Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins followed by substrate addition and measured after 3 hrs by PPiLight Inorganic Pyrophosphate assay kit method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4345255
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.35 | 5.04 | 5.04 |
| 269.14 | 3.07 | 3.07 |
| 295.17 | 3.61 | 3.61 |
| 316.36 | 1.85 | 1.85 |
| 311.39 | 3.90 | 3.90 |
| 257.34 | 2.30 | 2.30 |
| 295.39 | 3.68 | 3.68 |
| 193.25 | 0.70 | 0.70 |
| 294.40 | 4.13 | 4.13 |
| 293.16 | 3.59 | 3.59 |
| 279.13 | 3.29 | 3.29 |
| 243.31 | 2.27 | 2.27 |
| 308.17 | 4.13 | 4.13 |
| 238.29 | 2.60 | 2.60 |
| 335.45 | 4.46 | 4.46 |
| 210.24 | 1.98 | 1.98 |
| 296.37 | 3.21 | 3.21 |
| 230.27 | 1.68 | 1.68 |
| 331.37 | 3.93 | 3.93 |
| 269.35 | 3.37 | 3.37 |
| 291.35 | 3.87 | 3.87 |
| 255.32 | 2.18 | 2.18 |
| 310.40 | 3.47 | 3.47 |
| 228.30 | 2.38 | 2.38 |
| 294.15 | 2.87 | 2.87 |
| 216.24 | 1.89 | 1.89 |
| 227.31 | 2.99 | 2.99 |
| 309.41 | 4.07 | 4.07 |
| 231.30 | 1.61 | 1.61 |
| 167.22 | 0.17 | 0.17 |
| 255.32 | 1.66 | 1.66 |
| 244.30 | 2.24 | 2.24 |
| 311.17 | 3.45 | 3.45 |
| 278.14 | 4.12 | 4.12 |
| 207.28 | 1.09 | 1.09 |
| 292.17 | 4.43 | 4.43 |
| 321.42 | 4.07 | 4.07 |
| 279.13 | 3.29 | 3.29 |
| 244.30 | 2.51 | 2.51 |
| 331.44 | 3.10 | 3.10 |
| 323.44 | 4.32 | 4.32 |
| 243.31 | 2.46 | 2.46 |
| 221.31 | 1.85 | 1.85 |
| 253.35 | 3.31 | 3.31 |