Basic Information
ID: ALA4345302
Type: Binding
Description: Inhibition of human recombinant full length His-tagged Bcr-Abl expressed in baculovirus expression system using tyrosine-2 peptide as substrate after 1 hr in presence of 10 mM ATP by FRET based Z'-LYTE assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Bcr/Abl fusion protein(ALA2096618)
Document: ALA4342493
Inhibition of human recombinant full length His-tagged Bcr-Abl expressed in baculovirus expression system using tyrosine-2 peptide as substrate after 1 hr in presence of 10 mM ATP by FRET based Z'-LYTE assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4345302
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 546.60 | 4.71 | 4.71 |
| 518.51 | 7.34 | 7.34 |
| 486.50 | 6.90 | 6.90 |
| 518.51 | 7.34 | 7.34 |
| 520.94 | 7.55 | 7.55 |
| 514.55 | 7.46 | 7.46 |
| 472.47 | 6.64 | 6.64 |
| 516.52 | 6.91 | 6.91 |
| 500.52 | 7.21 | 7.21 |
| 598.67 | 6.64 | 6.64 |
| 518.51 | 7.34 | 7.34 |
| 500.52 | 7.46 | 7.46 |
| 486.50 | 6.90 | 6.90 |
| 500.52 | 7.21 | 7.21 |
| 530.68 | 5.63 | 5.63 |
| 518.51 | 7.34 | 7.34 |
| 500.52 | 7.21 | 7.21 |
| 598.67 | 6.64 | 6.64 |
| 542.61 | 8.19 | 8.19 |
| 504.49 | 7.04 | 7.04 |
| 486.50 | 6.90 | 6.90 |
| 511.51 | 6.77 | 6.77 |
| 418.50 | 5.88 | 5.88 |
| 500.52 | 7.21 | 7.21 |
| 528.58 | 8.02 | 8.02 |