Basic Information
ID: ALA4345328
Type: Binding
Description: Agonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged beta-arrestin2 assessed as increase in beta-arrestin2 recruitment measured after 5 mins in presence of coelenterazine H by BRET assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Dopamine D2 receptor(ALA217)
Document: ALA4342494
Agonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged beta-arrestin2 assessed as increase in beta-arrestin2 recruitment measured after 5 mins in presence of coelenterazine H by BRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4345328
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 267.33 | 2.85 | 2.85 |
| 279.34 | 3.17 | 3.17 |
| 295.38 | 3.63 | 3.63 |
| 351.40 | 3.29 | 3.29 |
| 457.53 | 4.96 | 4.96 |
| 379.46 | 3.85 | 3.85 |
| 430.30 | 4.05 | 4.05 |
| 323.44 | 4.02 | 4.02 |
| 323.44 | 4.02 | 4.02 |
| 374.28 | 4.22 | 4.22 |
| 307.39 | 3.95 | 3.95 |
| 374.28 | 4.22 | 4.22 |
| 365.43 | 3.60 | 3.60 |
| 393.48 | 4.41 | 4.41 |
| 379.46 | 4.07 | 4.07 |
| 374.28 | 4.22 | 4.22 |
| 374.28 | 4.22 | 4.22 |
| 385.85 | 3.94 | 3.94 |
| 309.41 | 3.76 | 3.76 |
| 355.43 | 3.40 | 3.40 |