Basic Information
ID: ALA4345360
Type: Binding
Description: Poison activity at human topo2alpha assessed as induction of accumulation of topo-2/DNA cleavage complex formation at 200 uM using pBR233 plasmid incubated for 6 mins by by SYBR safe DNA stain based cleavage complex formation assay
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA4342496
Poison activity at human topo2alpha assessed as induction of accumulation of topo-2/DNA cleavage complex formation at 200 uM using pBR233 plasmid incubated for 6 mins by by SYBR safe DNA stain based cleavage complex formation assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4345360
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 481.48 | 4.92 | 4.92 |
| 499.47 | 5.21 | 5.21 |
| 465.48 | 5.25 | 5.25 |