Basic Information
ID: ALA4345397
Type: Binding
Description: Inhibition of TNKS/TNKS2 (unknown origin) expressed in human DLD1 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4345397
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 529.97 | 4.48 | 4.48 |
| 431.44 | 0.92 | 0.92 |
| 415.44 | 1.95 | 1.95 |
| 415.44 | 1.89 | 1.89 |
| 539.66 | 1.43 | 1.43 |
| 493.54 | 1.32 | 1.32 |
| 440.52 | 1.87 | 1.87 |
| 445.47 | 1.31 | 1.31 |
| 482.56 | 1.64 | 1.64 |
| 416.47 | 2.28 | 2.28 |
| 510.61 | 2.42 | 2.42 |
| 484.58 | 1.75 | 1.75 |
| 429.43 | 1.42 | 1.42 |
| 457.51 | 1.18 | 1.18 |
| 475.50 | 0.67 | 0.67 |
| 459.45 | 1.40 | 1.40 |
| 471.49 | 1.27 | 1.27 |
| 459.50 | 1.96 | 1.96 |
| 480.59 | 2.80 | 2.80 |
| 427.48 | 1.81 | 1.81 |
| 483.44 | 2.88 | 2.88 |
| 524.64 | 2.67 | 2.67 |
| 431.49 | 1.78 | 1.78 |
| 510.61 | 2.28 | 2.28 |
| 440.45 | 1.84 | 1.84 |
| 509.63 | 1.99 | 1.99 |
| 526.61 | 1.52 | 1.52 |
| 510.61 | 2.28 | 2.28 |
| 430.46 | 1.80 | 1.80 |
| 417.46 | 1.39 | 1.39 |
| 426.47 | 2.86 | 2.86 |
| 471.53 | 1.83 | 1.83 |
| 481.58 | 1.22 | 1.22 |
| 471.51 | 1.96 | 1.96 |
| 495.60 | 1.56 | 1.56 |
| 440.45 | 2.39 | 2.39 |