Basic Information
ID: ALA4345583
Type: ADME
Description: Activation of recombinant human C-terminal 6xHis-tagged ClpP expressed in Escherichia coli assessed as induction of casein degradation at 0.1 to 1 uM using FITC-labelled casein as substrate pretreated with enzyme for 30 mins followed by substrate addition and measured every 3 mins for 3 hrs in absence of AAA+ chaperone by fluorescence based tecan-plate reader assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4345583
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 489.95 | 3.65 | 3.65 |
| 397.95 | 3.80 | 3.80 |
| 397.95 | 3.80 | 3.80 |
| 345.46 | 2.99 | 2.99 |
| 413.46 | 4.01 | 4.01 |