Basic Information
ID: ALA4345634
Type: Binding
Description: Inhibition of HDAC1/2 in human HeLa cell nuclear extracts pre-incubated for 5 mins before fluorogenic substrate Boc-Lys (acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC addition and measured after 30 mins by fluorescence based assay
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA4345634
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 376.42 | 3.34 | 3.34 |
| 560.50 | ||
| 689.67 | ||
| 650.63 | ||
| 575.52 | ||
| 689.67 | ||
| 560.50 | ||
| 614.55 | ||
| 640.59 | ||
| 575.52 | ||
| 640.59 | ||
| 511.43 | ||
| 614.55 | ||
| 650.63 | ||
| 511.43 |