Assay Report Card

Basic Information

ID: ALA4345744

Type: Binding

Description: Activation of LATS1 in human MDA-MB-231 cells assessed as induction of YAP degradation by measuring suppression of YAP protein expression at 0.5 uM pretreated with compound for 24 hrs followed by incubation with protein synthesis inhibitor, CHX up to 48 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: MDA-MB-231

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
635.997.337.33