Basic Information
ID: ALA4345864
Type: Binding
Description: Selectivity index, ratio of IC50 for GST-tagged human RET expressed in baculovirus to IC50 for recombinant N-Terminal GST-tagged human RET V804M mutant (658 to end residues)
Format: BAO_0000019
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4342511
Selectivity index, ratio of IC50 for GST-tagged human RET expressed in baculovirus to IC50 for recombinant N-Terminal GST-tagged human RET V804M mutant (658 to end residues): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4345864
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 475.36 | 4.43 | 4.43 |
| 501.51 | 5.54 | 5.54 |
| 344.37 | 3.74 | 3.74 |
| 358.41 | 3.36 | 3.36 |
| 324.39 | 1.47 | 1.47 |
| 345.36 | 3.13 | 3.13 |
| 372.43 | 3.11 | 3.11 |
| 298.30 | 1.53 | 1.53 |
| 344.38 | 2.50 | 2.50 |
| 365.44 | 3.02 | 3.02 |
| 341.38 | 3.28 | 3.28 |
| 394.46 | 2.77 | 2.77 |
| 351.41 | 2.54 | 2.54 |
| 344.38 | 2.50 | 2.50 |
| 380.43 | 2.05 | 2.05 |
| 325.37 | 2.10 | 2.10 |
| 331.34 | 3.26 | 3.26 |
| 301.35 | 3.40 | 3.40 |
| 358.41 | 3.36 | 3.36 |
| 345.36 | 3.13 | 3.13 |
| 337.38 | 2.29 | 2.29 |
| 339.40 | 2.49 | 2.49 |
| 344.38 | 2.50 | 2.50 |
| 345.36 | 3.10 | 3.10 |