Basic Information
ID: ALA4345866
Type: Binding
Description: Inhibition of RET V804M mutant (unknown origin)expressed in human BaF3 cells assessed as reduction in cell viability incubated for 48 hrs by celltiter glo luminescence cell viability assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: BaF3
Target: Tyrosine-protein kinase receptor RET(ALA2041)
Document: ALA4342511
Inhibition of RET V804M mutant (unknown origin)expressed in human BaF3 cells assessed as reduction in cell viability incubated for 48 hrs by celltiter glo luminescence cell viability assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4345866
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 475.36 | 4.43 | 4.43 |
| 501.51 | 5.54 | 5.54 |
| 324.39 | 1.47 | 1.47 |
| 345.36 | 3.13 | 3.13 |
| 298.30 | 1.53 | 1.53 |
| 344.38 | 2.50 | 2.50 |
| 341.38 | 3.28 | 3.28 |
| 351.41 | 2.54 | 2.54 |
| 344.38 | 2.50 | 2.50 |
| 380.43 | 2.05 | 2.05 |
| 325.37 | 2.10 | 2.10 |
| 345.36 | 3.13 | 3.13 |
| 339.40 | 2.49 | 2.49 |
| 344.38 | 2.50 | 2.50 |