Basic Information
ID: ALA4345982
Type: Toxicity
Description: Selectivity index, ratio of CC50 for cytotoxicity in human TZM-bl assessed as reduction in cell viability incubated for 1 day by Cyto-tox-Glo cytotoxicity assay to EC50 for antiviral activity against HIV1 NL4-3 infected in human TZM-bl cells assessed as reduction in virus induced cytopathogenicity incubated for 1 day by luciferase reporter gene assay
Activity Charts
Bioactivity
Activity Types for Assay ALA4345982
Ratio CC50/EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.53 | 4.41 | 4.41 |
| 522.58 | 2.62 | 2.62 |
| 609.66 | 1.83 | 1.83 |
| 599.11 | 2.57 | 2.57 |
| 495.60 | 2.67 | 2.67 |
| 526.57 | 2.27 | 2.27 |
| 582.65 | 2.06 | 2.06 |
| 579.68 | 1.50 | 1.50 |
| 496.59 | 1.95 | 1.95 |
| 516.02 | 3.02 | 3.02 |
| 511.60 | 2.37 | 2.37 |
| 509.63 | 2.98 | 2.98 |
| 564.66 | 1.92 | 1.92 |
| 582.65 | 2.06 | 2.06 |
| 499.56 | 2.50 | 2.50 |
| 925.86 | 5.18 | 5.18 |
| 552.61 | 2.63 | 2.63 |
| 496.59 | 1.95 | 1.95 |
| 579.68 | 1.50 | 1.50 |
| 609.66 | 1.83 | 1.83 |
| 594.69 | 1.93 | 1.93 |
| 607.82 | 5.73 | 5.73 |
| 560.47 | 3.13 | 3.13 |
| 881.41 | 5.07 | 5.07 |
| 526.57 | 2.27 | 2.27 |
| 582.65 | 2.06 | 2.06 |
| 523.66 | 3.29 | 3.29 |
| 481.57 | 2.36 | 2.36 |
| 496.59 | 1.95 | 1.95 |
| 864.95 | 4.55 | 4.55 |
| 609.66 | 1.83 | 1.83 |
| 499.56 | 2.50 | 2.50 |
| 579.68 | 1.50 | 1.50 |
| 536.61 | 2.93 | 2.93 |
| 643.56 | 2.68 | 2.68 |
| 499.56 | 2.50 | 2.50 |
| 578.69 | 2.23 | 2.23 |