Basic Information
ID: ALA4346048
Type: Binding
Description: Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells at 10 uM using Histone H3 peptide (1 to 21) and [3H]acetyl-CoA as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured after 30 mins by scintillation counting method relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Histone acetyltransferase p300(ALA3784)
Document: ALA4342520
Inhibition of recombinant human GST-tagged p300 HAT domain (1195 to 1673 residues) expressed in Escherichia coli BL21 codon plus cells at 10 uM using Histone H3 peptide (1 to 21) and [3H]acetyl-CoA as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured after 30 mins by scintillation counting method relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4346048
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 514.74 | 8.51 | 8.51 |
| 446.70 | 7.08 | 7.08 |
| 447.69 | 7.51 | 7.51 |
| 420.63 | 4.09 | 4.09 |
| 342.46 | 4.36 | 4.36 |
| 475.74 | 8.19 | 8.19 |
| 422.59 | 5.70 | 5.70 |
| 433.62 | 5.50 | 5.50 |
| 474.76 | 7.86 | 7.86 |
| 490.61 | 6.42 | 6.42 |
| 343.54 | 4.20 | 4.20 |
| 357.52 | 3.84 | 3.84 |
| 482.65 | 5.21 | 5.21 |
| 422.59 | 4.16 | 4.16 |
| 530.78 | 5.51 | 5.51 |
| 447.69 | 5.93 | 5.93 |