Basic Information
ID: ALA4346119
Type: Binding
Description: Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 2 hrs by fluorescence based micro plate reader analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: Histone deacetylase 6(ALA1865)
Document: ALA4342521
Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 2 hrs by fluorescence based micro plate reader analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4346119
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 349.43 | 3.33 | 3.33 |
| 284.36 | 2.91 | 2.91 |
| 478.52 | 3.45 | 3.45 |
| 504.55 | 3.85 | 3.85 |
| 588.72 | 6.15 | 6.15 |
| 578.63 | 2.92 | 2.92 |
| 516.56 | 3.95 | 3.95 |
| 505.54 | 2.40 | 2.40 |
| 548.56 | 3.01 | 3.01 |
| 560.66 | 5.37 | 5.37 |
| 574.69 | 5.76 | 5.76 |
| 297.36 | 2.58 | 2.58 |
| 515.54 | 3.36 | 3.36 |
| 532.61 | 4.58 | 4.58 |
| 464.61 | 5.10 | 5.10 |
| 546.63 | 4.98 | 4.98 |
| 530.59 | 4.34 | 4.34 |
| 478.52 | 3.45 | 3.45 |
| 283.38 | 2.94 | 2.94 |
| 490.53 | 3.41 | 3.41 |
| 464.61 | 5.10 | 5.10 |
| 397.52 | 4.27 | 4.27 |
| 490.65 | 5.50 | 5.50 |
| 411.42 | 2.62 | 2.62 |