Basic Information
ID: ALA4346334
Type: Binding
Description: Inhibition of human N-terminal His6 tagged BRD4 BD2 (352 to 457) residues expressed in Escherichia coli BL21(DE3) cells after 1 hr by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4346334
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 501.51 | 3.76 | 3.76 |
| 473.46 | 3.11 | 3.11 |
| 491.56 | 5.06 | 5.06 |
| 572.48 | 4.94 | 4.94 |
| 472.55 | 4.65 | 4.65 |
| 518.60 | 4.05 | 4.05 |
| 501.63 | 5.70 | 5.70 |
| 516.62 | 4.33 | 4.33 |
| 486.57 | 4.44 | 4.44 |
| 529.61 | 5.59 | 5.59 |
| 549.69 | 5.48 | 5.48 |
| 413.52 | 4.49 | 4.49 |
| 515.54 | 4.15 | 4.15 |
| 511.58 | 4.32 | 4.32 |
| 519.62 | 5.84 | 5.84 |
| 533.60 | 4.83 | 4.83 |
| 491.61 | 4.36 | 4.36 |
| 490.54 | 4.79 | 4.79 |
| 507.61 | 4.49 | 4.49 |
| 507.61 | 4.49 | 4.49 |
| 503.57 | 5.20 | 5.20 |
| 518.64 | 4.08 | 4.08 |
| 540.62 | 4.59 | 4.59 |
| 473.57 | 4.92 | 4.92 |
| 528.03 | 4.83 | 4.83 |
| 493.59 | 4.18 | 4.18 |
| 494.57 | 3.34 | 3.34 |
| 493.59 | 4.10 | 4.10 |
| 553.58 | 5.84 | 5.84 |
| 522.63 | 4.45 | 4.45 |
| 506.53 | 5.01 | 5.01 |
| 477.59 | 4.05 | 4.05 |
| 561.58 | 5.20 | 5.20 |
| 542.06 | 5.14 | 5.14 |
| 514.00 | 4.52 | 4.52 |
| 515.54 | 4.10 | 4.10 |
| 477.54 | 4.67 | 4.67 |
| 445.52 | 4.18 | 4.18 |
| 535.67 | 5.17 | 5.17 |
| 503.57 | 5.20 | 5.20 |
| 502.60 | 4.23 | 4.23 |
| 519.62 | 4.63 | 4.63 |
| 492.60 | 4.05 | 4.05 |
| 459.50 | 4.39 | 4.39 |
| 573.59 | 6.38 | 6.38 |
| 543.59 | 5.12 | 5.12 |
| 505.55 | 4.05 | 4.05 |
| 525.60 | 4.63 | 4.63 |
| 502.60 | 4.02 | 4.02 |