Assay Report Card

Basic Information

ID: ALA4346408

Type: Unassigned

Description: Ratio of solubility of the compound in pH 7.1 buffer measured after 24 hrs to IC50 for antagonist activity at recombinant human TAS2R8 expressed in cells co-expressing Galpha16gust44 assessed as inhibition of andrographolide-induced intracellular calcium level

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
425.451.961.96
409.452.992.99
411.421.571.57
381.392.212.21
395.422.602.60
407.432.742.74
383.382.642.64
421.463.133.13
395.422.512.51
395.422.602.60