ID: ALA4346420
Type: Functional
Description: Reversible antagonist activity at recombinant human TAS2R8 assessed as recovery of suppression of andrographolide-induced intracellular calcium level at 1 uM preincubated for 60 secs followed by andrographolide addition measured after 5 mins washout period using Fura-2AM dye by cell-based fluorescent microscopic analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Taste receptor type 2 member 8(ALA3988599)
Document: ALA4342523
Reversible antagonist activity at recombinant human TAS2R8 assessed as recovery of suppression of andrographolide-induced intracellular calcium level at 1 uM preincubated for 60 secs followed by andrographolide addition measured after 5 mins washout period using Fura-2AM dye by cell-based fluorescent microscopic analysis: 1
Bioactivity
Activity Types for Assay ALA4346420
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
381.39 | 2.21 | 2.21 |