Assay Report Card

Basic Information

ID: ALA4346420

Type: Functional

Description: Reversible antagonist activity at recombinant human TAS2R8 assessed as recovery of suppression of andrographolide-induced intracellular calcium level at 1 uM preincubated for 60 secs followed by andrographolide addition measured after 5 mins washout period using Fura-2AM dye by cell-based fluorescent microscopic analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
381.392.212.21