Reversible antagonist activity at recombinant human TAS2R8 assessed as recovery of suppression of andrographolide-induced intracellular calcium level ...

Basic Information

ID: ALA4346420

Type: Functional

Description: Reversible antagonist activity at recombinant human TAS2R8 assessed as recovery of suppression of andrographolide-induced intracellular calcium level at 1 uM preincubated for 60 secs followed by andrographolide addition measured after 5 mins washout period using Fura-2AM dye by cell-based fluorescent microscopic analysis

Format: BAO_0000219

Organism: Homo sapiens

Target:  Taste receptor type 2 member 8(ALA3988599)

Document:  ALA4342523

Reversible antagonist activity at recombinant human TAS2R8 assessed as recovery of suppression of andrographolide-induced intracellular calcium level at 1 uM preincubated for 60 secs followed by andrographolide addition measured after 5 mins washout period using Fura-2AM dye by cell-based fluorescent microscopic analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
381.392.212.21