Assay Report Card

Basic Information

ID: ALA4346421

Type: Functional

Description: Competitive antagonist activity at recombinant human TAS2R8 assessed as inhibition of andrographolide-induced intracellular calcium level at 3 to 3000 nM preincubated for 60 secs followed by varying levels of andrographolide addition using Fura-2AM dye by cell-based fluorescent microscopic analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
381.392.212.21