Basic Information
ID: ALA4346421
Type: Functional
Description: Competitive antagonist activity at recombinant human TAS2R8 assessed as inhibition of andrographolide-induced intracellular calcium level at 3 to 3000 nM preincubated for 60 secs followed by varying levels of andrographolide addition using Fura-2AM dye by cell-based fluorescent microscopic analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Taste receptor type 2 member 8(ALA3988599)
Document: ALA4342523
Competitive antagonist activity at recombinant human TAS2R8 assessed as inhibition of andrographolide-induced intracellular calcium level at 3 to 3000 nM preincubated for 60 secs followed by varying levels of andrographolide addition using Fura-2AM dye by cell-based fluorescent microscopic analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4346421
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.39 | 2.21 | 2.21 |