Basic Information
ID: ALA4346427
Type: Functional
Description: Antagonist activity at recombinant human TAS2R8 transiently expressed in HEK293T co-expressing Galpha16gust44 assessed as inhibition of andrographolide-induced intracellular calcium level by measuring remaining activity at 25 uM by fluo-4AM dye based FLIPR assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Taste receptor type 2 member 8(ALA3988599)
Document: ALA4342523
Antagonist activity at recombinant human TAS2R8 transiently expressed in HEK293T co-expressing Galpha16gust44 assessed as inhibition of andrographolide-induced intracellular calcium level by measuring remaining activity at 25 uM by fluo-4AM dye based FLIPR assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4346427
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 409.45 | 2.99 | 2.99 |
| 381.39 | 2.21 | 2.21 |