Basic Information
ID: ALA4346477
Type: Binding
Description: Activation of EPAC1 in HUVEC assessed as reduction in IL-6-promoted signaling by measuring pSTAT3 protein levels at 100 uM pre-incubated for 30 mins before IL6 and sIL6Ralpha stimulation for 5 hrs by Western blotting analysis
Organism: Homo sapiens
Cell type: HUVEC
Activity Charts
Bioactivity
Activity Types for Assay ALA4346477
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 515.51 | 5.19 | 5.19 |
| 374.39 | 2.44 | 2.44 |
| 416.46 | 2.32 | 2.32 |
| 369.44 | 3.34 | 3.34 |
| 404.38 | 2.77 | 2.77 |