Assay Report Card

Basic Information

ID: ALA4346479

Type: Binding

Description: Activation of EPAC1 in HUVEC assessed as reduction in IL-6-promoted signaling by measuring pAKT protein levels at 100 uM pre-incubated for 30 mins before IL6 and sIL6Ralpha stimulation for 5 hrs by Western blotting analysis

Organism: Homo sapiens

Cell type: HUVEC

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
374.392.442.44
416.462.322.32
404.382.772.77