Assay Report Card

Basic Information

ID: ALA4346482

Type: Binding

Description: Activation of EPAC1 in HUVEC assessed as reduction in IL-6-promoted signaling by measuring SELE protein expression at 100 uM pre-incubated for 30 mins before IL6 and sIL6Ralpha stimulation for 5 hrs by Western blotting analysis

Organism: Homo sapiens

Cell type: HUVEC

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
515.515.195.19
374.392.442.44
416.462.322.32
404.382.772.77