Basic Information
ID: ALA4347274
Type: Binding
Description: Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx at 100 uM incubated for 10 mins prior to CA addition by Fluo-4-AM dye based fluorescence assay relative to CA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Transient receptor potential cation channel subfamily A member 1(ALA6007)
Document: ALA4346663
Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx at 100 uM incubated for 10 mins prior to CA addition by Fluo-4-AM dye based fluorescence assay relative to CA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4347274
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.34 | 3.05 | 3.05 |
| 245.28 | 1.78 | 1.78 |
| 269.30 | 2.96 | 2.96 |
| 267.28 | 3.04 | 3.04 |
| 297.31 | 3.05 | 3.05 |
| 297.31 | 3.05 | 3.05 |
| 335.28 | 4.06 | 4.06 |
| 346.18 | 3.80 | 3.80 |
| 301.73 | 3.69 | 3.69 |
| 281.31 | 3.43 | 3.43 |
| 343.38 | 4.56 | 4.56 |
| 312.28 | 2.94 | 2.94 |
| 299.33 | 2.96 | 2.96 |
| 283.28 | 2.74 | 2.74 |
| 301.73 | 3.69 | 3.69 |
| 327.34 | 3.14 | 3.14 |
| 281.31 | 3.35 | 3.35 |
| 285.27 | 3.18 | 3.18 |
| 259.30 | 2.17 | 2.17 |