Basic Information
ID: ALA4347281
Type: Binding
Description: Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx at 3 uM incubated for 10 mins prior to CA challenge by Fluo-4-AM dye based fluorescence assay relative to calcimycin
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Transient receptor potential cation channel subfamily A member 1(ALA6007)
Document: ALA4346663
Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx at 3 uM incubated for 10 mins prior to CA challenge by Fluo-4-AM dye based fluorescence assay relative to calcimycin: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4347281
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 299.33 | 2.88 | 2.88 |
| 357.41 | 4.65 | 4.65 |
| 295.34 | 3.52 | 3.52 |
| 281.31 | 3.13 | 3.13 |