Antagonist activity at human TRPM8 expressed in HEK293 cells assessed as increase in calcium influx at 30 uM incubated for 10 mins prior to WS5 challe...

Basic Information

ID: ALA4347284

Type: Binding

Description: Antagonist activity at human TRPM8 expressed in HEK293 cells assessed as increase in calcium influx at 30 uM incubated for 10 mins prior to WS5 challenge by Fluo-4-AM dye based fluorescence assay relative to WS5

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293

Target:  Transient receptor potential cation channel subfamily M member 8(ALA1075319)

Document:  ALA4346663

Antagonist activity at human TRPM8 expressed in HEK293 cells assessed as increase in calcium influx at 30 uM incubated for 10 mins prior to WS5 challenge by Fluo-4-AM dye based fluorescence assay relative to WS5: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
299.332.882.88