Reversible desensitizing activity at human TRPA1 expressed in HEK293 cells assessed as CA-induced increase in Ca2+ influx up to 30 uM pretreated with ...

Basic Information

ID: ALA4347306

Type: Binding

Description: Reversible desensitizing activity at human TRPA1 expressed in HEK293 cells assessed as CA-induced increase in Ca2+ influx up to 30 uM pretreated with compound followed by drug wash-out and CA challenge by Fluo-4-AM dye based fluorescence assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293

Target:  Transient receptor potential cation channel subfamily A member 1(ALA6007)

Document:  ALA4346663

Reversible desensitizing activity at human TRPA1 expressed in HEK293 cells assessed as CA-induced increase in Ca2+ influx up to 30 uM pretreated with compound followed by drug wash-out and CA challenge by Fluo-4-AM dye based fluorescence assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
301.733.693.69
285.273.183.18